OLEIC ACID DERIVATIVES AS TREATMENTS FOR FRIEDREICH ATAXIA AND INHIBITORS OF FERROPTOSIS
The invention relates to compounds of Formula I or Formula II: to compositions comprising such compounds, and to methods of use thereof for treating neurodegenerative disorders, such as Friedreich ataxia.
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| Main Authors | , , , , , , |
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| Format | Patent |
| Language | English |
| Published |
26.01.2023
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The invention relates to compounds of Formula I or Formula II: to compositions comprising such compounds, and to methods of use thereof for treating neurodegenerative disorders, such as Friedreich ataxia. |
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| AbstractList | The invention relates to compounds of Formula I or Formula II: to compositions comprising such compounds, and to methods of use thereof for treating neurodegenerative disorders, such as Friedreich ataxia. |
| Author | XIA, Shujuan Huryn, Donna M WILSON, Robert B LEE, Taehee SMITH, Amos Cotticelli, Maria Grazia FORESTIERI, Roberto |
| Author_xml | – fullname: Huryn, Donna M – fullname: LEE, Taehee – fullname: WILSON, Robert B – fullname: Cotticelli, Maria Grazia – fullname: XIA, Shujuan – fullname: FORESTIERI, Roberto – fullname: SMITH, Amos |
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| RelatedCompanies | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA The Children's Hospital of Philadelphia |
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| Snippet | The invention relates to compounds of Formula I or Formula II: to compositions comprising such compounds, and to methods of use thereof for treating... |
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| SubjectTerms | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | OLEIC ACID DERIVATIVES AS TREATMENTS FOR FRIEDREICH ATAXIA AND INHIBITORS OF FERROPTOSIS |
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