METHODS AND SYSTEMS FOR SLOWING BRAIN ATROPHY

• Main Authors: Boasso, Alyssa, Konisky, Alex, Megerian, Tom, Malchano, Zach, Cotter, Colleen, Mrozak, Holly, Hagós, Mihály, Cimenser, Aylin, Strozewski, Nathan, Travers, Taylor, Williams, Martin, Vaughan, Brent, Kwan, Kim, Hempel, Evan
• Format: Patent
• Language: English
• Published: 26.01.2023
• Subjects: ELECTROTHERAPY; HUMAN NECESSITIES; HYGIENE; MAGNETOTHERAPY; MEDICAL OR VETERINARY SCIENCE; RADIATION THERAPY; ULTRASOUND THERAPY

Systems and methods of the present disclosure are directed to neural stimulation via non-invasive sensory stimuli. The non-invasive sensory stimuli can reduce neuroinflammation, improving synaptic plasticity and stimulating neural networking, and improving microglial-mediated clearance of cerebral insults, which would otherwise contribute to the progression of brain atrophy, by inducing synchronized gamma oscillations in at least one region of a brain in a subject. Stimulations can adjust, control or otherwise manage the frequency of the neural oscillations to provide beneficial effects to one or more cognitive states or cognitive functions of the brain, while mitigating or preventing adverse consequences on a cognitive state or cognitive function that stem from progression of brain atrophy.