TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

• Main Authors: Heald, Robert Andrew, Jones, Graham Elgin, McLean, Neville James, Dotson, Jennafer, Heffron, Timothy, Salphati, Laurent, Wei, BinQing, Ndubaku, Chudi, Olivero, Alan G, Wang, Lan, Krintel, Sussie Lerche
• Format: Patent
• Language: English
• Published: 03.11.2022
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Tricyclic PI3k inhibitor compounds of Formula I with anti-cancer activity, anti-inflammatory activity, or immunoregulatory properties, and more specifically with PI3 kinase modulating or inhibitory activity are described. Methods are described for using the tricyclic PI3K inhibitor compounds of Form...