CHIMERIC ANTIGEN RECEPTORS CONTAINING GLYPICAN 2 BINDING DOMAINS

The present disclosure is directed to chimeric antigen receptors binding to Glypican 2, nucleic acids encoding the same, and cells expressing the same, and methods of using such cells to treat cancers that express or overexpress the Glypican 2 antigen.

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Main Authors BARRETT, David, MACKALL, Crystal, JELEV, Dontcho V, HEITZENEDER, Sabine, MARIS, John, BOSSE, Kristopher, FOSTER, Jessica, DIMITROV, Dimiter, MAJZNER, Robbie, ZHU, ZHONGYU
Format Patent
LanguageEnglish
Published 18.08.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The present disclosure is directed to chimeric antigen receptors binding to Glypican 2, nucleic acids encoding the same, and cells expressing the same, and methods of using such cells to treat cancers that express or overexpress the Glypican 2 antigen.
AbstractList The present disclosure is directed to chimeric antigen receptors binding to Glypican 2, nucleic acids encoding the same, and cells expressing the same, and methods of using such cells to treat cancers that express or overexpress the Glypican 2 antigen.
Author DIMITROV, Dimiter
MARIS, John
ZHU, ZHONGYU
FOSTER, Jessica
BARRETT, David
HEITZENEDER, Sabine
JELEV, Dontcho V
MACKALL, Crystal
BOSSE, Kristopher
MAJZNER, Robbie
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– fullname: MARIS, John
– fullname: BOSSE, Kristopher
– fullname: FOSTER, Jessica
– fullname: DIMITROV, Dimiter
– fullname: MAJZNER, Robbie
– fullname: ZHU, ZHONGYU
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RelatedCompanies THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
The Children's Hospital of Philadelphia
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC
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Snippet The present disclosure is directed to chimeric antigen receptors binding to Glypican 2, nucleic acids encoding the same, and cells expressing the same, and...
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title CHIMERIC ANTIGEN RECEPTORS CONTAINING GLYPICAN 2 BINDING DOMAINS
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