COMPOSITIONS COMPRISING AN ENDONUCLEASE AND METHODS FOR PURIFYING AN ENDONUCLEASE

Provided are compositions comprising an endonuclease and methods for purifying an endonuclease. One aspect of the invention provides a composition comprising at least 100 mg of an untagged endonuclease having an A260/A280 absorbance ratio of from about X to about 0.8, wherein X is less than 0.8. Ano...

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Bibliographic Details
Main Authors Chan, Carol, Lyng, Robert John, Schmitke, Jennifer Louise
Format Patent
LanguageEnglish
Published 11.08.2022
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Summary:Provided are compositions comprising an endonuclease and methods for purifying an endonuclease. One aspect of the invention provides a composition comprising at least 100 mg of an untagged endonuclease having an A260/A280 absorbance ratio of from about X to about 0.8, wherein X is less than 0.8. Another aspect of the invention provides a composition, generated by contacting a composition comprising at least 100 mg of an untagged endonuclease having an A260/A280 absorbance ratio of from about X to about 0.8, wherein X is less than 0.8, with an endonuclease binding molecule, wherein the endonuclease and the endonuclease binding molecule form a protein effector.
Bibliography:Application Number: US202017425533