IMPLANTABLE DEPOTS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS
The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing...
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| Main Authors | , , , , , , , , , |
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| Format | Patent |
| Language | English |
| Published |
21.04.2022
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days. |
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| AbstractList | The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days. |
| Author | Boyd, Stephen W Ruane, Patrick H Feldstein, Michael Seet, Daniel Boon Lim Gifford, III, Hanson S Wang, Honglei Teu, Koon Kiat Luo, Jingnan Naga, Karun D Hancock, Jackie Joe |
| Author_xml | – fullname: Ruane, Patrick H – fullname: Luo, Jingnan – fullname: Boyd, Stephen W – fullname: Feldstein, Michael – fullname: Hancock, Jackie Joe – fullname: Wang, Honglei – fullname: Naga, Karun D – fullname: Seet, Daniel Boon Lim – fullname: Gifford, III, Hanson S – fullname: Teu, Koon Kiat |
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| Notes | Application Number: US202117454320 |
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| Snippet | The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments,... |
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| Title | IMPLANTABLE DEPOTS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS |
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