CHEMICAL COMPOSITIONS AND METHODS FOR ENHANCING TRANSDERMAL DELIVERY OF THERAPEUTIC AGENTS
The present application discloses chemical compositions and methods for enhancing the transdermal permeation of therapeutic agents through skin. The chemical compositions and methods of the invention can include combinations of a first fatty acid having about 14 or more carbon atoms and a second fat...
Saved in:
| Main Authors | , |
|---|---|
| Format | Patent |
| Language | English |
| Published |
07.04.2022
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The present application discloses chemical compositions and methods for enhancing the transdermal permeation of therapeutic agents through skin. The chemical compositions and methods of the invention can include combinations of a first fatty acid having about 14 or more carbon atoms and a second fatty acid having about 10 or less carbon atoms. These compositions are useful for the delivery of therapeutic agents, in particular hard to deliver drugs such as those that have fused rings, including ondansetron, and large drugs such as peptides. The compositions of the invention can be formulated as transdermal gels, lotions, creams, transdermal patches, sprays or mists. |
|---|---|
| AbstractList | The present application discloses chemical compositions and methods for enhancing the transdermal permeation of therapeutic agents through skin. The chemical compositions and methods of the invention can include combinations of a first fatty acid having about 14 or more carbon atoms and a second fatty acid having about 10 or less carbon atoms. These compositions are useful for the delivery of therapeutic agents, in particular hard to deliver drugs such as those that have fused rings, including ondansetron, and large drugs such as peptides. The compositions of the invention can be formulated as transdermal gels, lotions, creams, transdermal patches, sprays or mists. |
| Author | Kydonieus, Agis Valia, Kirti H |
| Author_xml | – fullname: Valia, Kirti H – fullname: Kydonieus, Agis |
| BookMark | eNqNy70KwjAUQOEMOvj3DhechbZSnC_JbRNokpLcCrqUInGStlDfHx18AKezfGcrVuM0po24S03WSGxAetv6aNh4FwGdAkusvYpQ-QDkNDppXA0c0EVFwX4XRY25UriBr4A1BWypYyMBa3Ic92L9HF5LOvy6E8eKWOpTmqc-LfPwSGN6910ssqLIszK7lJif_1Mfcrs0jw |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| ExternalDocumentID | US2022105075A1 |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_US2022105075A13 |
| IEDL.DBID | EVB |
| IngestDate | Fri Oct 04 05:03:11 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_US2022105075A13 |
| Notes | Application Number: US202117402807 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220407&DB=EPODOC&CC=US&NR=2022105075A1 |
| ParticipantIDs | epo_espacenet_US2022105075A1 |
| PublicationCentury | 2000 |
| PublicationDate | 20220407 |
| PublicationDateYYYYMMDD | 2022-04-07 |
| PublicationDate_xml | – month: 04 year: 2022 text: 20220407 day: 07 |
| PublicationDecade | 2020 |
| PublicationYear | 2022 |
| RelatedCompanies | InteguRx Therapeutics, LLC |
| RelatedCompanies_xml | – name: InteguRx Therapeutics, LLC |
| Score | 3.3932037 |
| Snippet | The present application discloses chemical compositions and methods for enhancing the transdermal permeation of therapeutic agents through skin. The chemical... |
| SourceID | epo |
| SourceType | Open Access Repository |
| SubjectTerms | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | CHEMICAL COMPOSITIONS AND METHODS FOR ENHANCING TRANSDERMAL DELIVERY OF THERAPEUTIC AGENTS |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220407&DB=EPODOC&locale=&CC=US&NR=2022105075A1 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED-GivqmU_FjSkDpW7GuWbs-DOmadJ3YtPRjTF_GunYgSDdcxX_fa9h0T3tLciQkR365u-TuAvBQdPSM6pmmoqraVmmeFaqlTy0VbQnER06nhl7HO_vC8FL6Mu6MG_C5iYWReUJ_ZHJERNQM8V7J83r5f4nFpG_l6jH7wKbFs5v0mLK2jttt3JOmwvo9HgYscBTH6aWxIiJJQ1UCBaSNttI-KtJmjQc-6tdxKcttoeKewEGI45XVKTSKsglHzubvtSYc-usnbyyu0bc6g_dN_gLiBH4YxEMZAkxswYjPEy9gMUGbjnDh1d53YkCSyBYx45GPXRh_HY549EYClyQej-yQp8nQIfaAiyQ-h3uXJ46n4iQnfzyZpPH2ivQL2CsXZXEJhOa5Np_Pp09moVNds7pGl1pans-6WmeWG9kVtHaNdL2bfAPHdVW6rpgt2Ku-votblMpVdieZ-QutzYhF |
| link.rule.ids | 230,309,783,888,25576,76876 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dT8IwEG8IGvFNUeMHahPN3hYnGxt7IGasHZuybtk6grwQxkZiYgaRGf99bw0oT7w1vfTSXvrr3bV3V4Qe846aamqqyGCqtmUtS3PZVGemDL4E4CPTZrpa5Tv7THcT7XXcGdfQ5zYXRtQJ_RHFEQFRc8B7Kc7r1f8lFhGxleun9AO6li8O7xFp4x2327AnDYn0ezQMSGBLtt1LYolFggamBChIC3ylAzCyjQoPdNSv8lJWu0rFOUGHIfArylNUy4smatjbv9ea6MjfPHlDc4O-9RmabOsXYDvwwyD2RAowthjBPuVuQGIMPh2mzK2i79gA88hiMaGRD0MIHXojGr3jwMHcpZEV0oR7NrYGlPH4HD04lNuuDJOc_slkmsS7K1IvUL1YFvklwlqWKYvFYvZs5KqmKmZX72qmkmXzrtKZZ3p6hVr7OF3vJ9-jhsv94XTosbcbdFyRRBiL0UL18us7vwUNXaZ3QrC_PqmLOA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=CHEMICAL+COMPOSITIONS+AND+METHODS+FOR+ENHANCING+TRANSDERMAL+DELIVERY+OF+THERAPEUTIC+AGENTS&rft.inventor=Valia%2C+Kirti+H&rft.inventor=Kydonieus%2C+Agis&rft.date=2022-04-07&rft.externalDBID=A1&rft.externalDocID=US2022105075A1 |