ASENAPINE-CONTAINING ADHESIVE PATCH
An object of the present invention is to provide an asenapine-containing patch having excellent adhesiveness and handleability, which can persistently provide sufficient medicinal effects by suppressing cold flow during storage or application while enhancing skin permeability using a silicone-based...
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| Main Authors | , , |
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| Format | Patent |
| Language | English |
| Published |
02.12.2021
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| Subjects | |
| Online Access | Get full text |
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| Abstract | An object of the present invention is to provide an asenapine-containing patch having excellent adhesiveness and handleability, which can persistently provide sufficient medicinal effects by suppressing cold flow during storage or application while enhancing skin permeability using a silicone-based pressure-sensitive adhesive base, and thereby maintaining the stability of the drug in the patch during storage, and maintaining an appropriate administration form for a long period of time. The present invention relates to a patch having a support and a pressure-sensitive adhesive layer, wherein the pressure-sensitive adhesive layer comprises asenapine and a silicone-based pressure-sensitive adhesive base, and the loss tangent (tan δ) of the pressure-sensitive adhesive layer is 0.75 to 1.5 at 1.0 Hz. |
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| AbstractList | An object of the present invention is to provide an asenapine-containing patch having excellent adhesiveness and handleability, which can persistently provide sufficient medicinal effects by suppressing cold flow during storage or application while enhancing skin permeability using a silicone-based pressure-sensitive adhesive base, and thereby maintaining the stability of the drug in the patch during storage, and maintaining an appropriate administration form for a long period of time. The present invention relates to a patch having a support and a pressure-sensitive adhesive layer, wherein the pressure-sensitive adhesive layer comprises asenapine and a silicone-based pressure-sensitive adhesive base, and the loss tangent (tan δ) of the pressure-sensitive adhesive layer is 0.75 to 1.5 at 1.0 Hz. |
| Author | Yukuhiro, Masaki Amano, Satoshi Takagi, Yuka |
| Author_xml | – fullname: Takagi, Yuka – fullname: Amano, Satoshi – fullname: Yukuhiro, Masaki |
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| Notes | Application Number: US201917281621 |
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| RelatedCompanies | Hisamitsu Pharmaceutical Co., Inc |
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| Snippet | An object of the present invention is to provide an asenapine-containing patch having excellent adhesiveness and handleability, which can persistently provide... |
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| Title | ASENAPINE-CONTAINING ADHESIVE PATCH |
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