METHOD FOR DIRECTING CELLULAR MIGRATION PATTERNS ON A BIOLOGICAL TISSUE
A contoured biological tissue for a bioprostheses, such as a cardiac/vascular patch or a bioprosthetic heart valve, and methods of contouring the tissue, are described. A predetermined pattern is provided on the tissue, comprising a plurality of ridges or depressions that are configured to facilitat...
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Main Author | |
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Format | Patent |
Language | English |
Published |
15.07.2021
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Subjects | |
Online Access | Get full text |
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Summary: | A contoured biological tissue for a bioprostheses, such as a cardiac/vascular patch or a bioprosthetic heart valve, and methods of contouring the tissue, are described. A predetermined pattern is provided on the tissue, comprising a plurality of ridges or depressions that are configured to facilitate cellular migration in a first direction and discourage cellular migration in a second direction. The biological tissue can be used in connection with a bioprosthetic heart valve comprising a biological tissue leaflet structure coupled to a supporting frame. |
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Bibliography: | Application Number: US202117216406 |