MEMBRANE FOR BLOOD PURIFICATION

• Main Authors: KRAUSE, Bernd, ZWEIGART, Carina, STORR, Markus, BOSCHETTI-DE-FIERRO, Adriana, BECK, Werner, VOIGT, Manuel, LOERCHER, Joachim, WOCHNER, Arnd, BEHR, Heinrich, HERBST, Philipp, BUCK, Reinhold, HORNUNG, Markus
• Format: Patent
• Language: English
• Published: 27.08.2020
• Subjects: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; SEPARATION; TRANSPORTING

The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.