KIF18A INHIBITORS

as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, a...

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Main Authors BANERJEE, Abhisek, FROHN, Michael J, LOW, Jonathan Dante, CHEN, Jian Jeffrey, MINATTI, Ana Elena, BROWN, James Alexander, BOURBEAU, Matthew Paul, LI, Kexue, JIA, Lei, PETTUS, Liping H, WALTON, Mary Catherine, MA, Vu, TAMAYO, Nuria A, LIU, Qingyian
Format Patent
LanguageEnglish
Published 30.07.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Abstract as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of KIF18A.
AbstractList as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of KIF18A.
Author CHEN, Jian Jeffrey
MA, Vu
LIU, Qingyian
WALTON, Mary Catherine
MINATTI, Ana Elena
BANERJEE, Abhisek
PETTUS, Liping H
LOW, Jonathan Dante
TAMAYO, Nuria A
BROWN, James Alexander
LI, Kexue
BOURBEAU, Matthew Paul
JIA, Lei
FROHN, Michael J
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– fullname: MINATTI, Ana Elena
– fullname: BROWN, James Alexander
– fullname: BOURBEAU, Matthew Paul
– fullname: LI, Kexue
– fullname: JIA, Lei
– fullname: PETTUS, Liping H
– fullname: WALTON, Mary Catherine
– fullname: MA, Vu
– fullname: TAMAYO, Nuria A
– fullname: LIU, Qingyian
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Snippet as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell...
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SourceType Open Access Repository
SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title KIF18A INHIBITORS
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