PROCESS FOR THE PREPARATION OF ARIPIPRAZOLE LAUROXIL

• Main Authors: POMARES MARCO, Marta, MARQUILLAS OLONDRIZ, Francisco De Asís, BESSA BELLMUNT, Jorge, DE LEÓN MARTÍN, Antonio Abelino
• Format: Patent
• Language: English
• Published: 07.05.2020
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

It is provided a process for the preparation of aripiprazole lauroxil that comprises reacting 1-(hydroxymethyl) aripiprazole with lauric acid in the presence of a suitable solvent and a carboxyl activating agent in the presence of a suitable solvent and, optionally, in the presence of an appropriate...