DETECTION OF NUCLEASE EDITED SEQUENCES IN AUTOMATED MODULES AND INSTRUMENTS

• Main Authors: Graige, Michael, Fox, Richard, Masquelier, Don, Chabansky, Bruce, Belgrader, Phillip, Garst, Andrew, Spindler, Eileen, Hiddessen, Amy
• Format: Patent
• Language: English
• Published: 20.02.2020
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules-including high throughput modules-for screening cells that have been subjected to editing and identifying and selecting cells th...