IMMUNOMODULATORY ONCOLYTIC ADENOVIRAL VECTORS, AND METHODS OF PRODUCTION AND USE THEREOF FOR TREATMENT OF CANCER

• Main Authors: STEINER, Philipp, HICKLIN, Daniel, SEIDEL-DUGAN, Cynthia, WILLS, Kenneth Nelson, WINSTON, William
• Format: Patent
• Language: English
• Published: 09.01.2020
• Subjects: ELECTRIC COMMUNICATION TECHNIQUE; ELECTRICITY; TELEPHONIC COMMUNICATION

Disclosed herein are compositions and methods for treating cancer in a subject. This involves administering an oncolytic virus containing a heterologous DNA sequence encoding one or more immunomodulatory and/or immunostimulatory polypeptide(s) of interest to the subject under conditions effective to...