METHODS FOR AFFINITY-BASED NON-ANTIBODY CAPTURE AND PURIFICATION OF EXTRACELLULAR VESICLES

A method is disclosed to capture and purify extracellular vesicles from biofluids via lipid affinity-based capture. The EVTRAP (Extracellular Vesicles Total Recovery And Purification) method enables capture of EVs onto modified beads. The EVTRAP method results in fast and reproducible capture and is...

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Bibliographic Details
Main Authors Ilyuk, Anton, Tao, Weiguo A
Format Patent
LanguageEnglish
Published 03.10.2019
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:A method is disclosed to capture and purify extracellular vesicles from biofluids via lipid affinity-based capture. The EVTRAP (Extracellular Vesicles Total Recovery And Purification) method enables capture of EVs onto modified beads. The EVTRAP method results in fast and reproducible capture and isolation of EVs with greater than 90% recovery yields.
Bibliography:Application Number: US201916374713