METHOD FOR DIAGNOSIS OF COLORECTAL CANCER USING MASS SPECTROMETRY OF N-GLYCANS

The present invention relates to a method of diagnosing colorectal cancer by detection of glycan changes, and more particularly to a method of diagnosing colorectal cancer using mass spectrometry, in which, when specific glycan structures increase, decrease or significantly change due to a change in...

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Bibliographic Details
Main Authors Oh, Myung Jin, Lee, Sung Hyeon, Park, Seung Yeol, Lee, Ju A, Kim, Jung Hoe, An, Hyun Joo, Kim, Jae-Han, Kim, Jin Man
Format Patent
LanguageEnglish
Published 14.06.2018
Subjects
CHEMISTRY
DERIVATIVES THEREOF
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PHYSICS
SUGARS
TESTING
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Summary:The present invention relates to a method of diagnosing colorectal cancer by detection of glycan changes, and more particularly to a method of diagnosing colorectal cancer using mass spectrometry, in which, when specific glycan structures increase, decrease or significantly change due to a change in N-linked glycosylation of a colorectal cancer patient-derived glycoprotein, as detected by mass spectrometry, the glycan structures are selected as diagnostic markers.
Bibliography:Application Number: US201515580662