NEW MICROORGANISM AND METHOD FOR THE PRODUCTION OF 1.2-PROPANEDIOL BASED ON NADPH DEPENDENT ACETOL REDUCTASE AND IMPROVED NADPH SUPPLY

• Main Authors: SOUCAILLE Philippe, BESTEL CORRE Gwénaëlle, ALIPRANDI Pascale, NAVARRO Emilie, RAYNAUD Céline
• Format: Patent
• Language: English
• Published: 25.05.2017
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present invention relates to a recombinant microorganism useful for the production of 1,2-propanediol and process for the preparation of 1,2-propanediol. The microorganism of the invention is modified in a way that the 1,2-propanediol production is improved by enhancing NADPH dependent HAR activ...