THIENOMETHYLPIPERAZINE DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE

• Main Authors: SCHIFFER Alexander, GOERLITZER Jochen, STROBEL Hartmut, LORENZ Katrin, WANG Li-hsing, BREITSCHOPF Kristin, MENDEZ-PEREZ Maria
• Format: Patent
• Language: English
• Published: 10.11.2016
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The present invention relates to compounds of the formula I, wherein R1, R2, R3, R4 and X have the meanings indicated in the claims. The compounds of formula I are valuable pharmacologically active compounds. They are highly potent and selective soluble epoxide hydrolase inhibitors and are suitable,...