RECOMBINANT ANTIGENS OF THE PORCINE CIRCOVIRUS 2 (PCV-2) FOR VACCINE FORMULATIONS AND USE THEREOF

• Main Authors: ANDRADE TEIXEIRA JACKSON DE, DE MORAIS MONTEIRO ANTÔNIO, JUNIOR ABELARDO SILVA, ONOFRE THIAGO SOUZA, CRISPIM JOSICELLI SOUZA, AMAZILES SILVA LEITE ROBERTA, FIALHO GONZAGA NATÁLIA, VIDIGAL PEDRO MARCUS PEREIRA, KALKS STHEFANY PATARELI, JAQUEL ZILCH TIAGO, SALGADO RAFAEL LOCATELLI, FAUSTO MARIANA COSTA, FIETTO JULIANA LOPES RANGEL, DE ALMEIDA MÁRCIA ROGÉRIA, DE CRUZ SOUZA AMANDA MARTINS, BRESSAN GUSTAVO COSTA, LINO DE SOUZA LUIZ FERNANDO
• Format: Patent
• Language: English
• Published: 21.01.2016
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present continuation-in-part of the Application BR 7 10 2013 001893 refers to the obtainment of the viral capsid recombinant antigen of the Porcine circovirus 2 (PCV-2) and modifications thereof, upon expression in prokaryotic system, recovery of virus-like particles (VLPs) and its use in vaccine formulations. The antigens and vaccine formulations can be used in the immunization of animals in control programs of the diseases associated with PCV-2 in conventional swine production systems and represent alternatives to vaccines available on the market.