Polymeric Compound Having Camptothecin Compound And Anti-Cancer Effect Enhancer Bound Thereto, And Use of Same

The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single molecule, whereby it becomes possible to reduce the toxicity to normal cells and deliver and release the t...

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Main Authors OKAZAKI MANAMI, YAMAMOTO KEIICHIRO
Format Patent
LanguageEnglish
Published 15.10.2015
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Abstract The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single molecule, whereby it becomes possible to reduce the toxicity to normal cells and deliver and release the two components to an affected area with high efficiency to thereby improve the pharmacological efficacy of the two components. Provided is a polymeric compound represented by general formula (1).
AbstractList The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single molecule, whereby it becomes possible to reduce the toxicity to normal cells and deliver and release the two components to an affected area with high efficiency to thereby improve the pharmacological efficacy of the two components. Provided is a polymeric compound represented by general formula (1).
Author YAMAMOTO KEIICHIRO
OKAZAKI MANAMI
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Snippet The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a...
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Title Polymeric Compound Having Camptothecin Compound And Anti-Cancer Effect Enhancer Bound Thereto, And Use of Same
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