Hydroxybenzamide Derivatives And Their Use As Inhibitors Of HSP90

• Main Authors: FREDERICKSON MARTYN, NAVARRO EVA FIGUEROA, CONGREVE MILES STUART, WOOLFORD ALISON JO-ANNE, CHESSARI GIANNI, MURRAY CHRISTOPHER WILLIAM
• Format: Patent
• Language: English
• Published: 12.02.2015
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention provides compounds of the formula (I): or salts, tautomers, solvates and N-oxides thereof; wherein R1 is hydroxy or hydrogen; R2 is hydroxy; methoxy or hydrogen; provided that at least one of R1 and R2 is hydroxy; R3 is selected from hydrogen; halogen; cyano; optionally substituted C1-...