HETEROCYCLIC COMPOUNDS AS IMAGING PROBES OF TAU PATHOLOGY

• Main Authors: MOKKAPATI UMAMAHESHWAR P, JONES CLARE, NEWINGTON IAN MARTIN, JOSE JINTO, JOHANSSON SAGA, GLASER MATTHIAS EBERHARD, WYNN DUNCAN, RANGSWAMY CHITRALEKHA, NAIRNE JAMES
• Format: Patent
• Language: English
• Published: 01.01.2015
• Subjects: APPARATUS THEREFOR; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; TESTING

Pyridazinone compounds of Formula I: (I) wherein: R′ is alkyl or Ar, optionally substituted with at least one alkyl, halogen, hydroxyl, alkoxy, haloalkoxy, acid, ester, amino, nitro, amide, or alkoxyhalo; 2 R is independently alkyi, alkynyl, ester, amino, amide, acid, aryl, heteroaryl, aminoalkyl, -...