LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM

Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I). The invention also relates to com...

Full description

Saved in:
Bibliographic Details
Main Authors BOWMAN KEITH, LABONTE TANZINA, BARYZA JEREMY, WEST LAURA, LEE CAMERON, ZHAO JUNPING, VARGEESE CHANDRA, GEALL ANDREW
Format Patent
LanguageEnglish
Published 16.10.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

Abstract Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I). The invention also relates to compositions and uses for stealth lipids of formula (XI). Also provided are processes for making such compounds, compositions, and formulations, plus methods and uses of such compounds, compositions, and formulations to deliver biologically active agents to cells and/or tissues.
AbstractList Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I). The invention also relates to compositions and uses for stealth lipids of formula (XI). Also provided are processes for making such compounds, compositions, and formulations, plus methods and uses of such compounds, compositions, and formulations to deliver biologically active agents to cells and/or tissues.
Author WEST LAURA
BARYZA JEREMY
LEE CAMERON
LABONTE TANZINA
VARGEESE CHANDRA
ZHAO JUNPING
BOWMAN KEITH
GEALL ANDREW
Author_xml – fullname: BOWMAN KEITH
– fullname: LABONTE TANZINA
– fullname: BARYZA JEREMY
– fullname: WEST LAURA
– fullname: LEE CAMERON
– fullname: ZHAO JUNPING
– fullname: VARGEESE CHANDRA
– fullname: GEALL ANDREW
BookMark eNrjYmDJy89L5WQw9fEM8HQJ1lEA0wrO_r4B_sGeIZ7-fkAxRz8XBV_XEA9_l2AFfzeF0GBPP3eFEA9XXx4G1rTEnOJUXijNzaDs5hri7KGbWpAfn1pckJicmpdaEh8abGRgaGJsYGlkbu5oaEycKgB3Eyoa
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
ExternalDocumentID US2014309277A1
GroupedDBID EVB
ID FETCH-epo_espacenet_US2014309277A13
IEDL.DBID EVB
IngestDate Fri Jul 19 15:44:47 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_US2014309277A13
Notes Application Number: US201414197124
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141016&DB=EPODOC&CC=US&NR=2014309277A1
ParticipantIDs epo_espacenet_US2014309277A1
PublicationCentury 2000
PublicationDate 20141016
PublicationDateYYYYMMDD 2014-10-16
PublicationDate_xml – month: 10
  year: 2014
  text: 20141016
  day: 16
PublicationDecade 2010
PublicationYear 2014
RelatedCompanies WEST LAURA
BARYZA JEREMY
LEE CAMERON
LABONTE TANZINA
VARGEESE CHANDRA
ZHAO JUNPING
BOWMAN KEITH
GEALL ANDREW
NOVARTIS AG
RelatedCompanies_xml – name: GEALL ANDREW
– name: ZHAO JUNPING
– name: BOWMAN KEITH
– name: LEE CAMERON
– name: WEST LAURA
– name: NOVARTIS AG
– name: LABONTE TANZINA
– name: BARYZA JEREMY
– name: VARGEESE CHANDRA
Score 2.9545238
Snippet Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or...
SourceID epo
SourceType Open Access Repository
SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141016&DB=EPODOC&locale=&CC=US&NR=2014309277A1
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1bS8MwFD6MKeqbTsXplIDSpxVXm_TyUGRrWjuhF2wnextN14Ig3XAV_75J6HRPe8oNcoMvJ99JzjkAD5xTFELsqVVObJXzDazmuWarRGeVhZfEtJkwFA4jI5jh1zmZd-Bzawsj_YT-SOeIHFEFx3sjz-v1vxKLyr-Vm0f2watWz37mUKVlx-LTomYodOJ4SUxjV3FdZ5Yq0Zts00f2k2mOOVc64BdpU-DBe58Iu5T1rlDxT-Ew4f3VzRl0yroHx-429loPjsL2yZtnW_RtzoFwFj6l6RDJFLlxmMTpVNoBD9E4oij0siCmKYp9JMJpvKAs8MILuPe9zA1UPv7ib7mLWbo7Wf0SuvWqLq8AaZhYTGgtDWzh3NQthkc6qZZ5UbAqN40-DPb1dL2_-QZORFGcy5oxgG7z9V3ecoHbsDu5T78xKn26
link.rule.ids 230,309,783,888,25576,76876
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_GFOebTsWPqQGlTyuuNunHw5CtaW11bYftZG-j6VoQpBuu4r9vEjbd054ScnD5gLvLL7kPgHuOKXJh9tQyI7bK8QZWs0yzVaKz0sJzYtpMBAqHkeFP8MuUTBvwuYmFkXlCf2RyRC5ROZf3Wurr5f8jFpW-lasH9sGHFk9e2qfKGh0Lp0XNUOiw745jGjuK4_QniRK9SZresx9Nc8Cx0h6_ZJtCHtz3oYhLWW4bFe8I9secX1UfQ6Oo2tByNrXX2nAQrr-8eXctfasTIByFBzTpItkiJw7HcRLIOOAuGkQUhW7qxzRBsYdEOY1nlPpueAp3nps6vsrnn_1tdzZJthern0GzWlTFOSANE4uJV0sDWzgzdYvhnk7KeZbnrMxM4wI6uzhd7ibfQstPw9FsFESvV3AoSEJHa0YHmvXXd3HNjW_NbuSZ_QJCPoCt
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=LIPIDS%2C+LIPID+COMPOSITIONS%2C+AND+METHODS+OF+USING+THEM&rft.inventor=BOWMAN+KEITH&rft.inventor=LABONTE+TANZINA&rft.inventor=BARYZA+JEREMY&rft.inventor=WEST+LAURA&rft.inventor=LEE+CAMERON&rft.inventor=ZHAO+JUNPING&rft.inventor=VARGEESE+CHANDRA&rft.inventor=GEALL+ANDREW&rft.date=2014-10-16&rft.externalDBID=A1&rft.externalDocID=US2014309277A1