PYRROLIDINE DERIVATIVES AS SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF

• Main Authors: FOWLER LINDSAY, TINSLEY JONATHON MARK, HORNE GRAEME, WREN STEPHEN PAUL, VAN WELL RENATE MARIA, STORER RICHARD, DORGAN COLIN RICHARD, CZEMERYS LOUISE, WILSON FRANCIS XAVIER
• Format: Patent
• Language: English
• Published: 13.03.2014
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

Disclosed are compounds of formula (I): or a pharmaceutically acceptable salt, derivative, solvate, isomer, tautomer, N-oxide, ester, prodrug, isotope or protected form thereof, which are of use as OGA inhibitors, for example in the treatment of various conditions and diseases, including neurodegene...