ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE

The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kgamma. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

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Main Authors HENDERSON JAMES A, LIAO YUSHENG, CAO JINGRONG, GREY RONALD LEE, LE TIRAN ARNAUD, COLLIER PHILIP N, DAVIES ROBERT J, BANDARAGE UPUL KEERTHI, GRILLOT ANNE-LAURE, KRUEGER ELAINE B, WANG JIAN, ARONOV ALEX, PIERCE ALBERT CHARLES, O'DOWD HARDWIN, COME JON H, NANTHAKUMAR SUGANTHINI S, MESSERSMITH DAVID
Format Patent
LanguageEnglish
Published 06.02.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Abstract The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kgamma. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
AbstractList The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kgamma. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
Author PIERCE ALBERT CHARLES
HENDERSON JAMES A
O'DOWD HARDWIN
COLLIER PHILIP N
GRILLOT ANNE-LAURE
ARONOV ALEX
COME JON H
WANG JIAN
DAVIES ROBERT J
NANTHAKUMAR SUGANTHINI S
CAO JINGRONG
BANDARAGE UPUL KEERTHI
GREY RONALD LEE
LE TIRAN ARNAUD
MESSERSMITH DAVID
KRUEGER ELAINE B
LIAO YUSHENG
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– fullname: DAVIES ROBERT J
– fullname: BANDARAGE UPUL KEERTHI
– fullname: GRILLOT ANNE-LAURE
– fullname: KRUEGER ELAINE B
– fullname: WANG JIAN
– fullname: ARONOV ALEX
– fullname: PIERCE ALBERT CHARLES
– fullname: O'DOWD HARDWIN
– fullname: COME JON H
– fullname: NANTHAKUMAR SUGANTHINI S
– fullname: MESSERSMITH DAVID
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Snippet The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kgamma. The invention also provides pharmaceutically acceptable...
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE
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