NOVEL LIPID TRIPEPTIDE-BASED HYDROGELATOR AND HYDROGEL

A hydrogel that includes an aqueous solution or an alcohol aqueous solution, and a hydrogelator containing a lipid peptide represented by Formula (1), or a pharmaceutically usable salt thereof. In Formula (1), R1 represents an aliphatic group having 9 to 21 carbon atoms; R2, R3, and R4 independently...

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Bibliographic Details
Main Authors GOTOH MASAHIRO, MARUYAMA TATSUO, KODA DAISUKE, MIYACHI NOBUHIDE, IWAMA TAKEHISA
Format Patent
LanguageEnglish
Published 08.08.2013
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Summary:A hydrogel that includes an aqueous solution or an alcohol aqueous solution, and a hydrogelator containing a lipid peptide represented by Formula (1), or a pharmaceutically usable salt thereof. In Formula (1), R1 represents an aliphatic group having 9 to 21 carbon atoms; R2, R3, and R4 independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms that optionally has a branched chain having 1 or 2 carbon atoms, a phenylmethyl group, or a -(CH2)n-X group, and at least one of R2, R3, and R4 represents a -(CH2)n-X group; n represents an integer from 1 to 4; and X represents an amino group, a guanidino group, a -CONH2 group, or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring that optionally has 1 to 3 nitrogen atoms.
Bibliography:Application Number: US201313784290