Multiple-variable dose regimen for treating TNFa-related disorders

Multiple-variable dose methods for treating TNFalpha-related disorders, including Crohn's disease and psoriasis, comprising administering TNFalpha inhibitors, including TNFalpha antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction o...

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Main Authors TAYLOR LORI K, PAULSON SUSAN K, GRANNEMAN GEORGE R, HOFFMAN REBECCA S, CHARTASH ELLIOT K, YAN PHILIP, PENG JOANNA Z
Format Patent
LanguageEnglish
Published 16.05.2013
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Multiple-variable dose methods for treating TNFalpha-related disorders, including Crohn's disease and psoriasis, comprising administering TNFalpha inhibitors, including TNFalpha antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.
AbstractList Multiple-variable dose methods for treating TNFalpha-related disorders, including Crohn's disease and psoriasis, comprising administering TNFalpha inhibitors, including TNFalpha antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.
Author PAULSON SUSAN K
YAN PHILIP
HOFFMAN REBECCA S
CHARTASH ELLIOT K
TAYLOR LORI K
GRANNEMAN GEORGE R
PENG JOANNA Z
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Snippet Multiple-variable dose methods for treating TNFalpha-related disorders, including Crohn's disease and psoriasis, comprising administering TNFalpha inhibitors,...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Multiple-variable dose regimen for treating TNFa-related disorders
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