Macrocyclic hepatitis C serine protease inhibitors

The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, o...

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Main Authors SHANLEY JASON P, LIU DONG, SHEIKH AHMAD, GAI YONGHUA, SUN YING, GRIEME TIM, GRAMPOVNIK DAVID J, KU YIYIN, OR YAT SUN, ENGSTROM KEN, MCDANIEL KEITH F, WAGAW SEBLE H, MEI JIANZHANG, KEMPF DALE J, CHEN HUI-JU
Format Patent
LanguageEnglish
Published 10.06.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
AbstractList The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
Author WAGAW SEBLE H
LIU DONG
MEI JIANZHANG
SUN YING
CHEN HUI-JU
MCDANIEL KEITH F
SHANLEY JASON P
KEMPF DALE J
KU YIYIN
GAI YONGHUA
GRIEME TIM
GRAMPOVNIK DAVID J
OR YAT SUN
SHEIKH AHMAD
ENGSTROM KEN
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– fullname: GRAMPOVNIK DAVID J
– fullname: KU YIYIN
– fullname: OR YAT SUN
– fullname: ENGSTROM KEN
– fullname: MCDANIEL KEITH F
– fullname: WAGAW SEBLE H
– fullname: MEI JIANZHANG
– fullname: KEMPF DALE J
– fullname: CHEN HUI-JU
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Snippet The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said...
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HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Macrocyclic hepatitis C serine protease inhibitors
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