ISOQUINOLINE COMPOUNDS

• Main Authors: NARASINGA RAO BYAPPANAHALLY N, DELONG MITCHELL A, SZNAIDMAN MARCOS L, PEEL MICHAEL, YINGLING JEFFREY D, RICHARDSON THOMAS E, PATEL PARESMA R, MURRAY CLARE LOUISE, HEASLEY BRIAN H, HUDSON CHRISTINE, OAKLEY ROBERT H, ECKHARDT ALLEN E
• Format: Patent
• Language: English
• Published: 15.04.2010
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Isoquinoline compounds with G are provided that influence, inhibit or reduce the action of a G-protein receptor kinase. Pharmaceutical compositions including therapeutically effective amounts of the isoquinoline compounds and pharmaceutically acceptable carriers are also provided. Various methods using the compounds and/or compositions to affect disease states or conditions such as cancer, osteoporosis and glaucoma are also provided.