Biodegradable polymeric materials providing controlled release of hydrophobic drugs from implantable devices

• Main Authors: LIM FLORENCIA, TANG YIWEN, HOSSAINY SYED F.A, TROLLSAS MIKAEL O, NGO MICHAEL H
• Format: Patent
• Language: English
• Published: 30.04.2009
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROSTHESES; THEIR PREPARATION OR CHEMICAL WORKING-UP; TREATMENT OR PROTECTION OF EYES OR EARS

The present invention is directed to polymeric materials (e.g., coatings) comprising biodegradable copolymers and implantable devices (e.g., drug-delivery stents) formed of such materials. The biodegradable copolymers are derived from at least two relatively polar monomers and at least one relativel...