2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE

This invention relates to an anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient. It was proved that the BEC 1 potassium channel inhibitor has an action to improve learning disorder and is useful as a preventive or therapeutic agent for diseases, preferably de...

Full description

Saved in:
Bibliographic Details
Main Authors KUBOTA HIDEKI, NAKATOU KAZUHIRO, NAKAI EIICHI, SUZUKI TAKESHI, YAHIRO KIYOSHI, MIYAKE AKIRA, MOCHIZUKI SHINOBU, MIURA MASANORI
Format Patent
LanguageEnglish
Published 18.09.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

Abstract This invention relates to an anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient. It was proved that the BEC 1 potassium channel inhibitor has an action to improve learning disorder and is useful as a preventive or therapeutic agent for diseases, preferably dementia, in which the BEC 1 potassium channel is considered to be concerned. Illustratively, it was confirmed by an in vivo test that the BEC 1 potassium channel inhibitor has an action to improve learning disorder. Also, it was found that a compound having 2,4,6-triamino-1,3,5-triazine has a BEC 1 potassium channel inhibitory action.
AbstractList This invention relates to an anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient. It was proved that the BEC 1 potassium channel inhibitor has an action to improve learning disorder and is useful as a preventive or therapeutic agent for diseases, preferably dementia, in which the BEC 1 potassium channel is considered to be concerned. Illustratively, it was confirmed by an in vivo test that the BEC 1 potassium channel inhibitor has an action to improve learning disorder. Also, it was found that a compound having 2,4,6-triamino-1,3,5-triazine has a BEC 1 potassium channel inhibitory action.
Author YAHIRO KIYOSHI
MOCHIZUKI SHINOBU
KUBOTA HIDEKI
NAKAI EIICHI
SUZUKI TAKESHI
MIYAKE AKIRA
NAKATOU KAZUHIRO
MIURA MASANORI
Author_xml – fullname: KUBOTA HIDEKI
– fullname: NAKATOU KAZUHIRO
– fullname: NAKAI EIICHI
– fullname: SUZUKI TAKESHI
– fullname: YAHIRO KIYOSHI
– fullname: MIYAKE AKIRA
– fullname: MOCHIZUKI SHINOBU
– fullname: MIURA MASANORI
BookMark eNrjYmDJy89L5WTQMNIx0THTDQnydPT19PPXNdQx1jEFc6M8_VwVXFyDPMMcQzzDXHkYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSXxosJGBgYWRkbm5hamjoTFxqgAtfiYb
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
ExternalDocumentID US2008227785A1
GroupedDBID EVB
ID FETCH-epo_espacenet_US2008227785A13
IEDL.DBID EVB
IngestDate Fri Jul 19 13:59:25 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_US2008227785A13
Notes Application Number: US20080027246
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080918&DB=EPODOC&CC=US&NR=2008227785A1
ParticipantIDs epo_espacenet_US2008227785A1
PublicationCentury 2000
PublicationDate 20080918
PublicationDateYYYYMMDD 2008-09-18
PublicationDate_xml – month: 09
  year: 2008
  text: 20080918
  day: 18
PublicationDecade 2000
PublicationYear 2008
RelatedCompanies ASTELLAS PHARMA INC
RelatedCompanies_xml – name: ASTELLAS PHARMA INC
Score 2.7174006
Snippet This invention relates to an anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient. It was proved that the BEC 1...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080918&DB=EPODOC&locale=&CC=US&NR=2008227785A1
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQAXa5zA2SwEdfgq4wSwb2UyyB-Vs3ydggzSIpLTnJwhK0UdjXz8wj1MQrwjSCiSEHthcGfE5oOfhwRGCOSgbm9xJweV2AGMRyAa-tLNZPygQK5du7hdi6qMF6xxbA6s9CzcXJ1jXA38XfWc3Z2TY0WM0vCCxnZGRubmHqCOwrsQIb0uag_OAa5gTal1KAXKm4CTKwBQDNyysRYmBKzRNm4HSG3b0mzMDhC53yBjKhua9YhEHDSMdEx0w3JAjY_fb089c11DHWMQVzozz9XBVcgH2yMMcQzzBXUQZlN9cQZw9doJXxcB_GhwYju89YjIEF2PdPlWBQSLZITUqzsLA0T0xMMklNNko0TU6yNE42Bro_JTnJ2FySQQafSVL4paUZuGDLHwwtZBhYSopKU2WBdWxJkhw4aAB0b3sA
link.rule.ids 230,309,783,888,25576,76876
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1bS8MwFD6MKc43nYqXqQOl-NDi1suaPhTZeqHVtR1bO4YvpYktCDKHq_j3PQ2r7mlvSQ7kBl9OvuRcAO6Rcuk9ykNfVinMGPIUA_EtUaVXEFowSozKUTgIB16iPi-0RQM-al8YHif0hwdHREQxxHvJz-vV_yOWzW0r14_0HZs-n9zYtIWaHRNUf0SwR6YziezIEizLTGZCOOUyWdZ1og2RK-3hJVuv8ODMR5VfympbqbhHsD_B_pblMTTyZRtaVp17rQ0HwebLG4sb9K1P4EEWVXEgxVOk334YSX1RETVeffVDp2sjJ5sPY3_unMKd68SWJ-GQ6d8K02S2PT_lDJrI_fNz6DKS04IQQ88yquZMzjRGDYUpSATeGFX0C-js6ulyt_gWWl4cjNOxH75cwWFtCtEnHWiWX9_5Nerbkt7wbfoFY7p98w
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=2%2C4%2C6-TRIAMINO-1%2C3%2C5-TRIAZINE+DERIVATIVE&rft.inventor=KUBOTA+HIDEKI&rft.inventor=NAKATOU+KAZUHIRO&rft.inventor=NAKAI+EIICHI&rft.inventor=SUZUKI+TAKESHI&rft.inventor=YAHIRO+KIYOSHI&rft.inventor=MIYAKE+AKIRA&rft.inventor=MOCHIZUKI+SHINOBU&rft.inventor=MIURA+MASANORI&rft.date=2008-09-18&rft.externalDBID=A1&rft.externalDocID=US2008227785A1