PROCESSES FOR PREPARATION OF 9,11 EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN

• Main Authors: MUCCIARIELLO GENNARO, KUNDA SASTRY A, ERB BERNHARD, BAEZ JULIO A, WIECZOREK JOSEPH, POZZO MARK J, WANG PING T, LIU CHIN, SING YUEN-LUNG L, NG JOHN S, ANDERSON DENNIS K, VANZANELLA FORTUNATO, LETENDRE LEO J, YONAN EDWARD E, LAWSON JON P
• Format: Patent
• Language: English
• Published: 15.03.2007
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; STEROIDS; VINEGAR; WINE

Multiple novel reaction schemes, novel process steps and novel intermediates are provided for the synthesis of epoxymexrenone and other compounds of Formula I wherein: -A-A- represents the group -CHR4-CHR5- or -CR4-CR5- -R3, R4 and R5 are independently selected from the group consisting of hydrogen,...