Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or host...
Saved in:
Main Authors | , , , , , , , , , |
---|---|
Format | Patent |
Language | English |
Published |
14.04.2005
|
Edition | 7 |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described. |
---|---|
AbstractList | Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described. |
Author | HUA YE JOHNSON THEODORE O CHU SHAO SONG EASTMAN BRIAN WALTER SKALITSKY DONALD JAMES HENDRICKSON THOMAS F LUU HIEP THE CHAN FORA P YANG YI REICH SIEGFRIED HEINZ |
Author_xml | – fullname: HUA YE – fullname: LUU HIEP THE – fullname: SKALITSKY DONALD JAMES – fullname: EASTMAN BRIAN WALTER – fullname: CHAN FORA P – fullname: REICH SIEGFRIED HEINZ – fullname: JOHNSON THEODORE O – fullname: YANG YI – fullname: CHU SHAO SONG – fullname: HENDRICKSON THOMAS F |
BookMark | eNqNjM0KwjAQhHPQg3_vEPCqkFYEr0UU7-q5LOmWLrS7IZsKvr0R-wCeZob5ZpZmxsK4MFRxokBeIsOLIvTWyxBk5EYtcPNLSomEdWdThxRt6CAO4HFM5PNgVMzVFx4gYSTo1bYSJ1jfnI2Srs28zRVuJl2Z7fXyON_2GKRGDfmQMdXPe-nc0Z1cURZVcfiP-gBNMURJ |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
Edition | 7 |
ExternalDocumentID | US2005080121A1 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_US2005080121A13 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 12:58:49 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_US2005080121A13 |
Notes | Application Number: US20030626827 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050414&DB=EPODOC&CC=US&NR=2005080121A1 |
ParticipantIDs | epo_espacenet_US2005080121A1 |
PublicationCentury | 2000 |
PublicationDate | 20050414 |
PublicationDateYYYYMMDD | 2005-04-14 |
PublicationDate_xml | – month: 04 year: 2005 text: 20050414 day: 14 |
PublicationDecade | 2000 |
PublicationYear | 2005 |
RelatedCompanies | AGOURON PHARMACEUTICALS, INC |
RelatedCompanies_xml | – name: AGOURON PHARMACEUTICALS, INC |
Score | 2.6213455 |
Snippet | Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050414&DB=EPODOC&locale=&CC=US&NR=2005080121A1 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_GFPVNp-LHlIDSJ4trm9n1YcjWbgxhH7hV9jaSLcXCyIrpEP97L1mne9pb2guhTXK5u-R3vwA8eoIn1OOB7QqX2XSeODZn85otGi710V7hLNDZyP3BSy-mb9P6tATLbS6M4Qn9NuSIqFFz1PfcrNfZ_yZWZLCV6pmn-Gr12p00I2sbHddr1KFW1G52RsNoGFph2IzH1uB9I9OrsdPCWOkAHWlfA8A6H22dl5LtGpXuKRyOsD2Zn0FJyAoch9u71ypw1C-OvLFYaJ86h7Ql8zTDocPR19jcJdGAcH0vkiJMLjZPBQbriZgjAJJ97u5Zk7USKNKV0VPdTD6CbmtRWf1ILKhUXcBDtzMJezZ-8-yvi2bxePcHvUsoy5UUV0CSAJ0AhgIM5Ggt0WzrAW8ELuOuv2gw5xqq-1q62S--hRNDZaq5D2kVyvnXWtyhkc75venbX8vkl3s |
link.rule.ids | 230,309,783,888,25578,76884 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dT8IwEL8QNOKbosYP1CaaPbnItiLbAzGwQVD5ioDhjazQxSWkLHbE-N97LUN54q3tNU2_rnfX3v0KcO9wFlGHeabN7dCks8gyWTgrm9y1aRXlFe4CFY3c7T21x_R1UpnkYLGJhdE4od8aHBE5aob8nurzOvm_xAq0b6V8ZDEWLZ9bo1pgbKzjSpla1AgateagH_R9w_dr46HRe1_T1Gls1dFW2kMl21VI-82PhopLSbaFSusI9gfYnkiPIcdFEQr-5u-1Ihx0sydvTGbcJ08gros0TnDpcPWVb-6CKIdw9S-SJKGYr3OZD9YD0U8AJPncvrMmK8mRpCqjprrefATV1qyy_BGYkLE8hbtWc-S3Tezz9G-KpuPh9gCdM8iLpeDnQCIPlYAQCWjI0XKk0NY95np2yOzq3A2tCyjtaulyN_kWCu1RtzPtvPTeruBQw5oqHERagnz6teLXKLBTdqPn-RcPnppr |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Antipicornaviral+compounds+and+compositions%2C+their+pharmaceutical+uses%2C+and+materials+for+their+synthesis&rft.inventor=HUA+YE&rft.inventor=LUU+HIEP+THE&rft.inventor=SKALITSKY+DONALD+JAMES&rft.inventor=EASTMAN+BRIAN+WALTER&rft.inventor=CHAN+FORA+P&rft.inventor=REICH+SIEGFRIED+HEINZ&rft.inventor=JOHNSON+THEODORE+O&rft.inventor=YANG+YI&rft.inventor=CHU+SHAO+SONG&rft.inventor=HENDRICKSON+THOMAS+F&rft.date=2005-04-14&rft.externalDBID=A1&rft.externalDocID=US2005080121A1 |