Substituted 11-phenyl-dibenzazepine compounds useful for the treatment or prevention of diseases characterized by abnormal cell proliferation

The present invention provides substituted 11-phenyl-dibenzazepine compounds which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell proliferation in situ as a therapeutic approach towards the treatment or prevention of dise...

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Main Authors MOUSSA ADEL M, HAIDAR REEM M, SUN MINGHUA, HALPERIN JOSE, KELLEHER EUGENE W, TAFT HEATHER N, ZELDIN MICHAEL H, LOMBARDY RICHARD JOHN, FLUCKIGER RUDOLF, GAO YING-DUO, BRUGNARA CARLO, CLIFFORD JOHN J, SACHDEVA YESH P, BELLOTT EMILE M
Format Patent
LanguageEnglish
Published 01.01.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Abstract The present invention provides substituted 11-phenyl-dibenzazepine compounds which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell proliferation in situ as a therapeutic approach towards the treatment or prevention of diseases characterized by abnormal cell proliferation, such as cancer.
AbstractList The present invention provides substituted 11-phenyl-dibenzazepine compounds which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell proliferation in situ as a therapeutic approach towards the treatment or prevention of diseases characterized by abnormal cell proliferation, such as cancer.
Author ZELDIN MICHAEL H
TAFT HEATHER N
FLUCKIGER RUDOLF
SUN MINGHUA
HALPERIN JOSE
BELLOTT EMILE M
MOUSSA ADEL M
GAO YING-DUO
SACHDEVA YESH P
LOMBARDY RICHARD JOHN
HAIDAR REEM M
BRUGNARA CARLO
CLIFFORD JOHN J
KELLEHER EUGENE W
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– fullname: CLIFFORD JOHN J
– fullname: SACHDEVA YESH P
– fullname: BELLOTT EMILE M
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Snippet The present invention provides substituted 11-phenyl-dibenzazepine compounds which are specific, potent and safe inhibitors of mammalian cell proliferation....
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HETEROCYCLIC COMPOUNDS
METALLURGY
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Title Substituted 11-phenyl-dibenzazepine compounds useful for the treatment or prevention of diseases characterized by abnormal cell proliferation
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