RET kinase inhibitors

• Main Authors: Andrews, Steven W, McKenney, Megan L, Pancaldi, Thomas Pierre Dino, Irvin, Thomas C, McFaddin, Elizabeth A, Condroski, Kevin R, Pilkington-Miksa, Michael Alexander, Kolakowski, Gabrielle R, Anderson, Erin D, Mouret, Tiphaine, Munchhof, Michael J, Kumar, Manoj, Pinto, Marta, Boldron, Christopher Pierre Albert Jean, McLean, Johnathan Alexander
• Format: Patent
• Language: English
• Published: 30.04.2024
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Disclosed herein are compounds of formula I:or a pharmaceutically acceptable salt thereof, where the variables are as defined herein. These compounds are useful in treating RET associated cancers. Formulations containing the compounds of formula I and methods of making the compounds of formula I are...