Method of detecting anti-Ri in a subject with a previous streptococcal infection
Provided are methods for diagnosing a disease in a subject with a previous streptococcal infection by determining the presence or absence of one or more autoantibodies in a biological sample from the subject, wherein the one or more autoantibodies recognize an antigen from a protein selected from th...
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| Main Authors | , |
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| Format | Patent |
| Language | English |
| Published |
26.09.2023
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Provided are methods for diagnosing a disease in a subject with a previous streptococcal infection by determining the presence or absence of one or more autoantibodies in a biological sample from the subject, wherein the one or more autoantibodies recognize an antigen from a protein selected from the group consisting of ELAVL2, ELAVL3, ELAVL4, Nova-1, Nova-2, Cdr1, Cdr2; and Cdr3. The presence of such autoantibodies is indicative of a positive diagosis for a post-streptococcal disease such as PANDAS, post-GABHS glomerulonephritis, rheumatic fever, autism and Syndenham's chorea. |
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| AbstractList | Provided are methods for diagnosing a disease in a subject with a previous streptococcal infection by determining the presence or absence of one or more autoantibodies in a biological sample from the subject, wherein the one or more autoantibodies recognize an antigen from a protein selected from the group consisting of ELAVL2, ELAVL3, ELAVL4, Nova-1, Nova-2, Cdr1, Cdr2; and Cdr3. The presence of such autoantibodies is indicative of a positive diagosis for a post-streptococcal disease such as PANDAS, post-GABHS glomerulonephritis, rheumatic fever, autism and Syndenham's chorea. |
| Author | Naides, Stanley J Popov, Joanna |
| Author_xml | – fullname: Naides, Stanley J – fullname: Popov, Joanna |
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| Notes | Application Number: US201816209100 |
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| RelatedCompanies | Quest Diagnostics Investments LLC |
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| Snippet | Provided are methods for diagnosing a disease in a subject with a previous streptococcal infection by determining the presence or absence of one or more... |
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| Title | Method of detecting anti-Ri in a subject with a previous streptococcal infection |
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