Methods of synthesizing substituted pyridinone-pyridinyl compounds
The present disclosure provides methods of synthesizing a compound of Formula (P)-I. The method proceeds through several different pathways including several novel chiral separations, a Sonogashira coupling, a zinc mediated reductive cyanation, as well as through various halide containing intermedia...
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| Main Authors | , |
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| Format | Patent |
| Language | English |
| Published |
26.09.2023
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present disclosure provides methods of synthesizing a compound of Formula (P)-I. The method proceeds through several different pathways including several novel chiral separations, a Sonogashira coupling, a zinc mediated reductive cyanation, as well as through various halide containing intermediates. Also disclosed is the multi-kilogram preparation of several novel intermediates. |
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| AbstractList | The present disclosure provides methods of synthesizing a compound of Formula (P)-I. The method proceeds through several different pathways including several novel chiral separations, a Sonogashira coupling, a zinc mediated reductive cyanation, as well as through various halide containing intermediates. Also disclosed is the multi-kilogram preparation of several novel intermediates. |
| Author | Decrescenzo, Gary A Springer, John Robert |
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| Snippet | The present disclosure provides methods of synthesizing a compound of Formula (P)-I. The method proceeds through several different pathways including several... |
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| Title | Methods of synthesizing substituted pyridinone-pyridinyl compounds |
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