Composition comprising a combined herb extract of Salvia plebia and red ginseng as active ingredients for preventing or treating a respiratory inflammation and the use thereof

• Main Authors: Kyung, Jongsu, Lee, Moon-Yong, Han, Chang Kyun, Gwak, Hyo-Min, Min, Hye-Jeong, Kim, Hyo Keun, Kim, Sung Won, Kim, Young-Sin, Kim, Seung-Hyung, Kim, Jong Han, In, Gyo, Shin, Han-Jae, Jang, Kyoung Hwa
• Format: Patent
• Language: English
• Published: 29.11.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a composition and health functional food for preventing and treating a respiratory inflammation disease using a mixed herbal mixture. Through various experiments, for example, determination of the cell number of BAL (bronchoalveolar lavage) (Experimental Example 1); Determination of CD11b+/Gr-1+ ratio in leukocyte within BAL fluid (Experimental Example 2); Determination of expressed RNA level of inflammatory cytokines in lung tissue (Experimental Example 3); Determination of expressed RNA level of inflammatory cytokines in BALF (Experimental Example 4); Lung histology (Experimental Example 5); Brief Clinical test (Experimental Example 7) etc, it has been verified that the inventive combined extract showed more potent inhibiting effect on respiratory inflammation disease than each herb extract. Therefore, the herbal extract of the present invention can be usefully used in a pharmaceutical composition, health functional food, and health supplement food for preventing and treating respiratory inflammation disease.