Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith

Provided herein are 1-oxo-isoindoline-5-carboxamide compounds having the following structure:wherein R1, R2, R3, R4 and n are as defined herein, compositions comprising an effective amount of a 1-oxo-isoindoline-5-carboxamide compound, and methods for treating or preventing disorders.

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Main Authors Perrin-Ninkovic, Sophie, Hansen, Joshua, Baculi, Frans, Peng, Sophie, Lu, Chin-Chun, Correa, Matthew D, Lu, Gang, Lebrun, Laurie A, Nagy, Mark A, Northcote, Katherine
Format Patent
LanguageEnglish
Published 19.04.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Provided herein are 1-oxo-isoindoline-5-carboxamide compounds having the following structure:wherein R1, R2, R3, R4 and n are as defined herein, compositions comprising an effective amount of a 1-oxo-isoindoline-5-carboxamide compound, and methods for treating or preventing disorders.
AbstractList Provided herein are 1-oxo-isoindoline-5-carboxamide compounds having the following structure:wherein R1, R2, R3, R4 and n are as defined herein, compositions comprising an effective amount of a 1-oxo-isoindoline-5-carboxamide compound, and methods for treating or preventing disorders.
Author Lu, Chin-Chun
Peng, Sophie
Lebrun, Laurie A
Perrin-Ninkovic, Sophie
Northcote, Katherine
Baculi, Frans
Lu, Gang
Hansen, Joshua
Nagy, Mark A
Correa, Matthew D
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– fullname: Lu, Chin-Chun
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– fullname: Lu, Gang
– fullname: Lebrun, Laurie A
– fullname: Nagy, Mark A
– fullname: Northcote, Katherine
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Snippet Provided herein are 1-oxo-isoindoline-5-carboxamide compounds having the following structure:wherein R1, R2, R3, R4 and n are as defined herein, compositions...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith
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