Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use

• Main Authors: Klein, Brian D, Twyman, Roy E, White, H. Steven, Cid-Núñez, José Maria, Ceusters, Marc André, Van Osselaer, Nancy Eulalie Sylvain, Trabanco-Suárez, Andrés Avelino, Lavreysen, Hilde, Pype, Stefan Maria Christiaan
• Format: Patent
• Language: English
• Published: 31.08.2021
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to combinations comprising a positive allosteric modulator ("PAM") of metabotropic glutamatergic receptor subtype 2 ("mGluR2") or a pharmaceutically acceptable salt or a solvate thereof, or an orthosteric agonist of metabotropic glutamatergic recepto...