Prolonged release pharmaceutical composition containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol
A pharmaceutical formulation for prolonged release of the active ingredient 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol or a pharmaceutically acceptable salt thereof in a matrix containing between 1 and 80 wt. % of at least one pharmaceutically acceptable hydrophilic or hydrophobic polymer as a...
Saved in:
Main Authors | , |
---|---|
Format | Patent |
Language | English |
Published |
18.05.2021
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | A pharmaceutical formulation for prolonged release of the active ingredient 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol or a pharmaceutically acceptable salt thereof in a matrix containing between 1 and 80 wt. % of at least one pharmaceutically acceptable hydrophilic or hydrophobic polymer as a matrix forming agent and exhibiting in vivo the following release rate: 3 to 35% by weight (based on 100% by weight active ingredient) 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 0.5 hours; 5 to 50% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 1 hour; 10 to 75% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 2 hours; 15 to 82% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 3 hours; 30 to 97% by weight 3-(3-dimethylaminol-1-ethyl-2-methyl-propyl)phenol released after 6 hours; more than 50% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 12 hours; more than 70% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 18 hours, and more than 80% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 24 hours. |
---|---|
AbstractList | A pharmaceutical formulation for prolonged release of the active ingredient 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol or a pharmaceutically acceptable salt thereof in a matrix containing between 1 and 80 wt. % of at least one pharmaceutically acceptable hydrophilic or hydrophobic polymer as a matrix forming agent and exhibiting in vivo the following release rate: 3 to 35% by weight (based on 100% by weight active ingredient) 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 0.5 hours; 5 to 50% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 1 hour; 10 to 75% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 2 hours; 15 to 82% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 3 hours; 30 to 97% by weight 3-(3-dimethylaminol-1-ethyl-2-methyl-propyl)phenol released after 6 hours; more than 50% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 12 hours; more than 70% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 18 hours, and more than 80% by weight 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol released after 24 hours. |
Author | Bartholomaeus, Johannes Ziegler, Iris |
Author_xml | – fullname: Ziegler, Iris – fullname: Bartholomaeus, Johannes |
BookMark | eNqNjb0KAjEQhFNo4d87xE6Lhcsdaq8oloJaS7hb7xaS3ZDE4t7eQ30Aq5lv-GCmasTCOFF0ieKEW2x0RIc2oQ6djd7W-MpUW6dr8UESZRIeOmdLTNzqClYVNOQxd72znljAwAeghO8KIUro3Tp0yOLmavy0LuHilzO1PB1vhzNgkAemMDwy5sf9akxR7Mxmuy-rf5w3yW5Cpg |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
ExternalDocumentID | US11007156B2 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_US11007156B23 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 13:10:08 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_US11007156B23 |
Notes | Application Number: US201916600974 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210518&DB=EPODOC&CC=US&NR=11007156B2 |
ParticipantIDs | epo_espacenet_US11007156B2 |
PublicationCentury | 2000 |
PublicationDate | 20210518 |
PublicationDateYYYYMMDD | 2021-05-18 |
PublicationDate_xml | – month: 05 year: 2021 text: 20210518 day: 18 |
PublicationDecade | 2020 |
PublicationYear | 2021 |
RelatedCompanies | GRUENENTHAL GMBH |
RelatedCompanies_xml | – name: GRUENENTHAL GMBH |
Score | 3.322191 |
Snippet | A pharmaceutical formulation for prolonged release of the active ingredient 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol or a pharmaceutically acceptable... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | Prolonged release pharmaceutical composition containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210518&DB=EPODOC&locale=&CC=US&NR=11007156B2 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1NS8NAEB1KFfWmVdH6QQQpeliszca2hyAkaShCP7Ct9FZ2s6lGShLaiPTfO7NNbS96SzawJLO8mbyd2TcAt5TaaiDdQaTVOeNCBYxUx5iqSssSMhBCq_N3uk_tEX8ZW-MCfK7Pwmid0G8tjoiIChDvmfbX6WYTy9O1lYsHGeFQ8uwPba-Ss2PkLxbC2XPsVr_n9dyK69qjQaX7apMyWh25ioPueod-o0lnv_Xm0KmUdDuk-Iew28fZ4uwICmFcgn133XmtBHudPOGNlzn2FscQ9efoqOL3UBnU6ASjj5F-bG9IG1QentdgGVSCvmr-YJjszmQqol7RS1z_KE6Q0OkbVmOrUYZ-NF3O7qngK5mdwI3fGrpthu88-TXQZDTYfJ55CsU4icMzMJQSypw2-VRVFZeiKSxJ8RnXgzd40JTnUP57nvJ_Dy_ggIxNWfTHxiUUs_lXeIXBOZPX2qo_cHWWUw |
link.rule.ids | 230,309,786,891,25594,76906 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT8JAEJ4QNOJNUaP4qokhetj46Fbg0JjQQlB5RcBwI7vdojWkbaDG8O-dWYpw0Vu7TTbtbL6Zfjuz3wBcUmqrjHQHkVbijAvlMVIdY-pWWpaQnhBanb_VfmgM-PPQGmbgc3kWRuuEfmtxRESUh3hPtL-OV5tYrq6tnN3IAIeix3rfdospO0b-YiGc3apd63bcjlN0HHvQK7ZfbVJGKyFXqaK73iiROi_9Or1V6VRKvB5S6juw2cXZwmQXMn6Yh5yz7LyWh61WmvDGyxR7sz0IulN0VOG7rwxqdILRx4g_1jekDSoPT2uwDCpBXzR_MEx2ZTIVUK_oOa5_EEZI6PQNu2eLUYZ-NJ5PrqngK5rsw0W91ncaDN959Gug0aC3-jzzALJhFPqHYCgllDmu8LG6VVyKirAkxWdcD17mXkUeQeHveQr_PTyHXKPfao6aT-2XY9gmw1NG_a58Atlk-uWfYqBO5Jm28A-htZlA |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Prolonged+release+pharmaceutical+composition+containing+3-%283-dimethylamino-1-ethyl-2-methyl-propyl%29phenol&rft.inventor=Ziegler%2C+Iris&rft.inventor=Bartholomaeus%2C+Johannes&rft.date=2021-05-18&rft.externalDBID=B2&rft.externalDocID=US11007156B2 |