Method for producing RNA compositions
The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the...
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| Main Authors | , , , , , , , |
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| Format | Patent |
| Language | English |
| Published |
19.05.2020
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the use of the inventive method in the manufacture of a medicament or a vaccine. Furthermore, the invention relates to compositions containing the RNA-comprising nanoparticle, and to pharmaceutical compositions comprising the same. |
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| AbstractList | The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the use of the inventive method in the manufacture of a medicament or a vaccine. Furthermore, the invention relates to compositions containing the RNA-comprising nanoparticle, and to pharmaceutical compositions comprising the same. |
| Author | Kreuz, Markus Eber, Fabian Johannes Sonntag, Michael Wiggenhorn, Michael Kolland, Katharina Mutzke, Thorsten Sewing, Stefanie Wagner, Wenke |
| Author_xml | – fullname: Sonntag, Michael – fullname: Mutzke, Thorsten – fullname: Eber, Fabian Johannes – fullname: Kolland, Katharina – fullname: Wiggenhorn, Michael – fullname: Kreuz, Markus – fullname: Wagner, Wenke – fullname: Sewing, Stefanie |
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| Snippet | The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or... |
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| Title | Method for producing RNA compositions |
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