Humanized anti-ACTH antibodies and use thereof

• Main Authors: Feldhaus, Andrew Lawrence, Dutzar, Benjamin H, Scalley-Kim, Michelle L, Anderson, Katie Olson, Mitchell, Danielle Marie, Fan, Pei, Allison, Daniel S, Stewart, Erica, Karasek, Charlie, Ojala, Ethan Wayne, Latham, John, McNeill, Patricia Dianne, Garcia-Martinez, Leon F, Mulligan, Jenny A, Smith, Jeffrey T. L
• Format: Patent
• Language: English
• Published: 28.01.2020
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention is directed to antibodies and fragments thereof having binding specificity for ACTH. Embodiments of this invention relate to the binding fragments of antibodies described herein, comprising the sequences of the VH, VL and/or CDR polypeptides described herein, and the polynucleo...