siRNA compounds comprising terminal substitutions
The invention relates to modified siRNA compounds which down-regulate target gene expression, to pharmaceutical compositions comprising such compounds and to methods of treating and/or preventing the incidence or severity of various diseases or conditions associated with the genes and/or symptoms as...
Saved in:
| Main Author | |
|---|---|
| Format | Patent |
| Language | English |
| Published |
03.12.2019
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The invention relates to modified siRNA compounds which down-regulate target gene expression, to pharmaceutical compositions comprising such compounds and to methods of treating and/or preventing the incidence or severity of various diseases or conditions associated with the genes and/or symptoms associated with such diseases or conditions. |
|---|---|
| AbstractList | The invention relates to modified siRNA compounds which down-regulate target gene expression, to pharmaceutical compositions comprising such compounds and to methods of treating and/or preventing the incidence or severity of various diseases or conditions associated with the genes and/or symptoms associated with such diseases or conditions. |
| Author | Avkin-Nachum, Sharon |
| Author_xml | – fullname: Avkin-Nachum, Sharon |
| BookMark | eNrjYmDJy89L5WQwLM4M8nNUSM7PLcgvzUspBrOKMosz89IVSlKLcjPzEnMUikuTiksyS0pLMvPzinkYWNMSc4pTeaE0N4Oim2uIs4duakF-fGpxQWJyal5qSXxosKGBiaWJmbGhk5ExMWoA3jguXg |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| ExternalDocumentID | US10494631B2 |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_US10494631B23 |
| IEDL.DBID | EVB |
| IngestDate | Fri Jul 19 14:59:22 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_US10494631B23 |
| Notes | Application Number: US201715642581 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191203&DB=EPODOC&CC=US&NR=10494631B2 |
| ParticipantIDs | epo_espacenet_US10494631B2 |
| PublicationCentury | 2000 |
| PublicationDate | 20191203 |
| PublicationDateYYYYMMDD | 2019-12-03 |
| PublicationDate_xml | – month: 12 year: 2019 text: 20191203 day: 03 |
| PublicationDecade | 2010 |
| PublicationYear | 2019 |
| RelatedCompanies | Quark Pharmaceuticals, Inc |
| RelatedCompanies_xml | – name: Quark Pharmaceuticals, Inc |
| Score | 3.2339551 |
| Snippet | The invention relates to modified siRNA compounds which down-regulate target gene expression, to pharmaceutical compositions comprising such compounds and to... |
| SourceID | epo |
| SourceType | Open Access Repository |
| SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| Title | siRNA compounds comprising terminal substitutions |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191203&DB=EPODOC&locale=&CC=US&NR=10494631B2 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_GFPVNp6LzgwrSt2LbpA19KGK_GMK6sa2yt9EsLWxIN2zFf99L6Jwv-nYkkC9y98slv8sBPDrCzHNTFIbFmW1QUXIjR1g0aIloX3icUBVfMUzdQUZf5868A-tdLIz6J_RLfY6IGrVEfW-Uvd7uL7Eixa2sn_gKizbPycyP9NY7RufDNokeBX48HkWjUA9DP5vq6UQmufWoS6wAzfUBHqOZpH_Fb4GMStn-hpTkFA7H2FrVnEGnqHpwHO4yr_XgaNg-eKPY6l59Dla9mqQvmuSAy1RItZJQRRF7tJbS8q7VaAfU47_cTRfwkMSzcGBg34ufiS6y6X6Y5BK61aYqrkBzic2EoEtmlw7lucdZSYnL8rw0BbeFdw39v9vp_1d5Aydy0RQ9g9xCt_n4LO4QZBt-r1bnGyo3ghE |
| link.rule.ids | 230,309,783,888,25578,76884 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LS8NAEB5KFetNq6L1FUFyC6bZTWIOQWweRG3S0of0VrLdBCqSFhPx7zu7pNaL3oZd2Bc78-3svABuTa6nqc4zrctsQ6M8Z1qKsKjRHNE-cxihMr4iTqxoSp9n5qwBb5tYGJkn9EsmR0SOWiC_V1Jer7efWL70rSzv2BKbVg_hxPXVWjtG5cPQier33GA48Aee6nnudKwmI1Hk1qEW6fZQXO_gE_te5NkPXnsiKmX9G1LCA9gd4mhFdQiNrGhDy9tUXmvDXlwbvJGsea88gm65HCWPivABF6WQSkkhiyL2KLVLy7tSohyQxn9xm47hJgwmXqTh3POfjc6n4-0yyQk0i1WRnYJiEcPmnC5sIzcpSx1m55RYdprmOmcGd86g8_c4nf86r6EVTeL-vP-UvJzDvjhA6apBLqBZfXxmlwi4FbuSJ_UNa0-FAQ |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=siRNA+compounds+comprising+terminal+substitutions&rft.inventor=Avkin-Nachum%2C+Sharon&rft.date=2019-12-03&rft.externalDBID=B2&rft.externalDocID=US10494631B2 |