(Aza)pyridopyrazolopyrimidinones and indazolopyrimidinones and their use
The present application relates to novel substituted (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or pro...
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Format | Patent |
Language | English |
Published |
16.10.2018
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Abstract | The present application relates to novel substituted (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of acute and recurrent bleeding in patients with or without underlying hereditary or acquired bleeding disorders, wherein the bleeding is associated with a disease or medical intervention selected from the group consisting of menorrhagia, postpartum hemorrhage, hemorrhagic shock, trauma, surgery, transplantation, stroke, liver diseases, hereditary angioedema, nosebleed, and synovitis and cartilage damage following hemarthrosis. |
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AbstractList | The present application relates to novel substituted (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of acute and recurrent bleeding in patients with or without underlying hereditary or acquired bleeding disorders, wherein the bleeding is associated with a disease or medical intervention selected from the group consisting of menorrhagia, postpartum hemorrhage, hemorrhagic shock, trauma, surgery, transplantation, stroke, liver diseases, hereditary angioedema, nosebleed, and synovitis and cartilage damage following hemarthrosis. |
Author | Schuhmacher, Joachim Sperzel, Michael Köbberling, Johannes Stegmann, Christian Burkhardt, Nils Schlemmer, Karl-Heinz Ellermann, Manuel Haßfeld, Jorma Beyer, Kristin Cancho-Grande, Yolanda Werner, Matthias Röhrig, Susanne Köllnberger, Maria Kinzel, Tom |
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Notes | Application Number: US201715416651 |
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Snippet | The present application relates to novel substituted (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones, to processes for their preparation, the... |
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Title | (Aza)pyridopyrazolopyrimidinones and indazolopyrimidinones and their use |
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