HIV inhibiting bicyclic pyrimidine derivatives

• Main Authors: Guillemont, Jerôme Emile Georges, Delest, Bruno Francois Marie, Janssen, Paul Adriaan Jan, Heeres, Jan, Lewi, Paulus Joannes, Paugam, Mikaël
• Format: Patent
• Language: English
• Published: 11.09.2018
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

HIV replication inhibitors of formula wherein -a1=a2-a3=a4- is -CH CH-CH CH-, -N CH-CH CH-, -N CH-N CH-, -N CH-CH N-, -N N-CH CH-; -b1=b2-b3=b4- is -CH CH-CH CH-, -N CH-CH CH-, -N CH-N CH-, -N CH-CH N-, -N N-CH CH-; n and m is 0-4, R1 is hydrogen; aryl; formyl; C1-6alkylcarbonyl; C1-6alkyl; C1-6alky...