2-(PYRIDINE-2-YLAMINO)PYRIDO[2,3-D]PYRIMIDINE-7-ONS

• Main Authors: BOOTH RICHARD JOHN, QUIN JOHN III, VANDERWEL SCOTT NORMAN, BARVIAN MARK ROBERT, SHEEHAN DEREK JAMES, TOOGOOD PETER LAURENCE, REPINE JOSEPH THOMAS, ZHOU HAIRONG
• Format: Patent
• Language: English; Russian; Ukrainian
• Published: 25.06.2007
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (cdk4). (I) Изобретение представляет замещенные 2-аминопиридины, которые могут использоваться...