Ophthalmic compositions containing a nitric oxide releasing prostamide
The present invention relates to a preservative free ophthalmic aqueous composition in the form of solution comprising 0.005% to 0.18% w/w hexanoic acid, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl este...
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| Main Authors | , , |
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| Format | Patent |
| Language | Chinese English |
| Published |
21.04.2024
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to a preservative free ophthalmic aqueous composition in the form of solution comprising 0.005% to 0.18% w/w hexanoic acid, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester, from 0.5% w/w to 1.5% w/w macrogol 15 hydroxystearate, wherein macrogol 15 hydroxystearate is the only solubilizing agent. |
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| AbstractList | The present invention relates to a preservative free ophthalmic aqueous composition in the form of solution comprising 0.005% to 0.18% w/w hexanoic acid, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester, from 0.5% w/w to 1.5% w/w macrogol 15 hydroxystearate, wherein macrogol 15 hydroxystearate is the only solubilizing agent. |
| Author | SALDO, JULIEN DO, MARINA WEINER, ALAN L |
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| Snippet | The present invention relates to a preservative free ophthalmic aqueous composition in the form of solution comprising 0.005% to 0.18% w/w hexanoic acid,... |
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| Title | Ophthalmic compositions containing a nitric oxide releasing prostamide |
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