Inhibitors of [alpha]v[beta]6 integrin

• Main Authors: ZHONG, CHENG, SVENSSON, MATS A, DAY, TYLER, TROAST, DAWN MARIE, SOSA, BRIAN, HICKEY, EUGENE, LIPPA, BLAISE SCOTT, BURSAVICH, MATTHEW GREGORY, ROGERS, BRUCE NELSEN, KONZE, KYLE DAVID, DOWLING, JAMES E, KIM, BYUNGCHAN, HARRISON, BRYCE ALDEN, BORTOLATO, ANDREA, LIN, FU-YANG, GERASYUTO, ALEKSEY IGOREVICH
• Format: Patent
• Language: Chinese; English
• Published: 21.03.2024
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.