Substituted 4-aminoisoindoline-1,3-dione compounds, compositions thereof, and methods of treatment therewith

Provided herein is a method of preparing 4-aminoisoindoline-1,3-dione compounds with the following structure:wherein R, Ring A, and n are defined herein. Further described herein are compositions comprising an effective amount of a 4-aminoisoindoline-1,3-dione compound and methods for treating or pr...

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Main Authors NAGY, MARK A, HANSEN, JOSHUA, HARRIS, ROY L, HUANG, DEHUA, ALEXANDER, MATTHEW D, KERCHER, TIMOTHY S, PLANTEVIN-KRENITSKY, VERONIQUE, LOPEZ-GIRONA, ANTONIA, CARRANCIO, SORAYA, CORREA, MATTHEW D, GRANT, VIRGINIA HEATHER SHARRON
Format Patent
LanguageChinese
English
Published 11.09.2023
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Abstract Provided herein is a method of preparing 4-aminoisoindoline-1,3-dione compounds with the following structure:wherein R, Ring A, and n are defined herein. Further described herein are compositions comprising an effective amount of a 4-aminoisoindoline-1,3-dione compound and methods for treating or preventing disorders.
AbstractList Provided herein is a method of preparing 4-aminoisoindoline-1,3-dione compounds with the following structure:wherein R, Ring A, and n are defined herein. Further described herein are compositions comprising an effective amount of a 4-aminoisoindoline-1,3-dione compound and methods for treating or preventing disorders.
Author ALEXANDER, MATTHEW D
CORREA, MATTHEW D
NAGY, MARK A
HANSEN, JOSHUA
HARRIS, ROY L
HUANG, DEHUA
LOPEZ-GIRONA, ANTONIA
CARRANCIO, SORAYA
KERCHER, TIMOTHY S
GRANT, VIRGINIA HEATHER SHARRON
PLANTEVIN-KRENITSKY, VERONIQUE
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– fullname: PLANTEVIN-KRENITSKY, VERONIQUE
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– fullname: CARRANCIO, SORAYA
– fullname: CORREA, MATTHEW D
– fullname: GRANT, VIRGINIA HEATHER SHARRON
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Snippet Provided herein is a method of preparing 4-aminoisoindoline-1,3-dione compounds with the following structure:wherein R, Ring A, and n are defined herein....
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Substituted 4-aminoisoindoline-1,3-dione compounds, compositions thereof, and methods of treatment therewith
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